國枝武和 | 國枝研究室（生体情報学II）

A Versatile Technique for Measuring the Stiffness of Small Organisms Based on Microscopic Observation of Cantilever Strain

Mon, 13 Apr 2026 00:00:00 +0000

生命科学DOKIDOKI研究室にクマムシ研究のマンガと記事を掲載いただきました

Tue, 31 Mar 2026 00:00:00 +0000

テルモ生命科学振興財団の生命科学DOKIDOKI研究室に、クマムシ研究をマンガでとりあげていただきました。
マンガには研究室でクマムシを飼育している様子も描いていただき、クマムシの紹介と研究の最先端を要領よくまとめていただいたレポート記事もおすすめです。

【招待講演】小平市ふれあい下水道館30周年記念講演会

Sat, 01 Nov 2025 00:00:00 +0000

2025年11月1日にルネこだいら（東京都小平市）で開催された小平市ふれあい下水道館様の開館30周年記念講演会にて「クマムシの謎と生命のフシギ」というタイトルで講演させていただきました。クマムシやヒルガタワムシは水の浄化にも関わっており、同館のキャラクター、ヒルガタワムちゃんの御縁で呼んでいただきました。講演会後は同館を見学させていただき、とても面白い経験でした。

講演会のポスター
 開館30周年記念講演の報告

【招待講演】第36回変異機構研究会・特別講演

Sun, 07 Sep 2025 00:00:00 +0000

2025年9月6-7日に大学セミナーハウス（東京都八王子市）で開催された日本環境変異原ゲノム学会・第36回変異機構研究会「夏の学校」にて「極限環境耐性動物クマムシから学ぶ放射線障害の克服機構」というタイトルで講演させていただきました。

國枝武和教授が着任しました

Tue, 01 Apr 2025 00:00:00 +0000

2025年4月1日付で、兵庫県立大学大学院理学研究科生命科学専攻生体情報学II講座の教授として、國枝武和が着任しました。本研究室では、前任の西谷秀男先生が築かれた基盤を引き継ぎつつ、新たな研究テーマとして「極限環境における生存ロジック（survival logics against extremes）」の解明を掲げ、本学の研究コミュニティにこれまでにない視点をもたらすべく活動してまいります。新たな体制となる当研究室を、今後ともどうぞよろしくお願いいたします。

Comparative Study of Gamma Radiation Tolerance between Desiccation-Sensitive and Desiccation-Tolerant Tardigrades

Sat, 01 Feb 2025 00:00:00 +0000

Sexual Dimorphism in the Tardigrade Paramacrobiotus Metropolitanus Transcriptome

Sat, 01 Jun 2024 00:00:00 +0000

Single-Step Generation of Homozygous Knockout/Knock-in Individuals in an Extremotolerant Parthenogenetic Tardigrade Using DIPA-CRISPR

Sat, 01 Jun 2024 00:00:00 +0000

The Major Inducible Small Heat Shock Protein HSP20-3 in the Tardigrade Ramazzottius Varieornatus Forms Filament-like Structures and Is an Active Chaperone

Thu, 01 Feb 2024 00:00:00 +0000

A Comparative Ultrastructure Study of the Tardigrade Ramazzottius Varieornatus in the Hydrated State, after Desiccation and during the Process of Rehydration

Mon, 01 Jan 2024 00:00:00 +0000

Considerations on the TardiVec-based Analyses of Tissue Specificity and Desiccation-Induced Supramolecular Structure of Target Proteins

Wed, 01 Nov 2023 00:00:00 +0000

Mblk-1/E93, an Ecdysone Related-Transcription Factor, Targets Synaptic Plasticity-Related Genes in the Honey Bee Mushroom Bodies

Thu, 01 Dec 2022 00:00:00 +0000

Application of CRISPR/Cas9 System and the Preferred No-Indel End-Joining Repair in Tardigrades

Sat, 01 Oct 2022 00:00:00 +0000

Stress-Dependent Cell Stiffening by Tardigrade Tolerance Proteins That Reversibly Form a Filamentous Network and Gel

Thu, 01 Sep 2022 00:00:00 +0000

Description of a Model Tardigrade Paramacrobiotus Metropolitanus Sp. Nov. (Eutardigrada) from Japan with a Summary of Its Life History, Reproduction and Genomics

Sun, 01 May 2022 00:00:00 +0000

Parallel Evolution of Trehalose Production Machinery in Anhydrobiotic Animals via Recurrent Gene Loss and Horizontal Transfer

Thu, 01 Jul 2021 00:00:00 +0000

Developmental Stage-Specific Distribution and Phosphorylation of Mblk-1, a Transcription Factor Involved in Ecdysteroid-Signaling in the Honey Bee Brain

Fri, 01 May 2020 00:00:00 +0000

Space Radiation Biology for Living in Space

Wed, 01 Jan 2020 00:00:00 +0000

Comparison of Sexual Reproductive Behaviors in Two Species of Macrobiotidae (Tardigrada: Eutardigrada)

Mon, 01 Apr 2019 00:00:00 +0000

Interleukin-11 Induces and Maintains Progenitors of Different Cell Lineages during Xenopus Tadpole Tail Regeneration

Fri, 01 Sep 2017 00:00:00 +0000

Comparative Genomics of the Tardigrades Hypsibius Dujardini and Ramazzottius Varieornatus

Sat, 01 Jul 2017 00:00:00 +0000

DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades

Thu, 01 Jun 2017 00:00:00 +0000

Gene Expression and Immunohistochemical Analyses of mKast Suggest Its Late Pupal and Adult-Specific Functions in the Honeybee Brain

Sun, 01 Jan 2017 00:00:00 +0000

Mblk-1 Transcription Factor Family: Its Roles in Various Animals and Regulation by NOL4 Splice Variants in Mammals

Sun, 01 Jan 2017 00:00:00 +0000

Acute Phase Response in Amputated Tail Stumps and Neural Tissue-Preferential Expression in Tail Bud Embryos of the Xenopus Neuronal Pentraxin I Gene

Thu, 01 Dec 2016 00:00:00 +0000

Extremotolerant Tardigrade Genome and Improved Radiotolerance of Human Cultured Cells by Tardigrade-Unique Protein

Thu, 01 Sep 2016 00:00:00 +0000

Novel Mitochondria-Targeted Heat-Soluble Proteins Identified in the Anhydrobiotic Tardigrade Improve Osmotic Tolerance of Human Cells

Thu, 01 Jan 2015 00:00:00 +0000

Suggested Involvement of PP1/PP2A Activity and De Novo Gene Expression in Anhydrobiotic Survival in a Tardigrade, Hypsibius Dujardini, by Chemical Genetic Approach

Thu, 01 Jan 2015 00:00:00 +0000

Unique Gene Expression Profile of the Proliferating Xenopus Tadpole Tail Blastema Cells Deciphered by RNA-sequencing Analysis

Thu, 01 Jan 2015 00:00:00 +0000

Splicing Variants of NOL4 Differentially Regulate the Transcription Activity of Mlr1 and Mlr2 in Cultured Cells

Sat, 01 Nov 2014 00:00:00 +0000

Identification and Characterization of an Egr Ortholog as a Neural Immediate Early Gene in the European Honeybee (Apis Mellifera L.)

Tue, 01 Oct 2013 00:00:00 +0000

Expression Analysis of XPhyH-like during Development and Tail Regeneration in Xenopus Tadpoles: Possible Role of XPhyH-like Expressing Immune Cells in Impaired Tail Regenerative Ability

Fri, 01 Feb 2013 00:00:00 +0000

Analysis of DNA Repair and Protection in the Tardigrade Ramazzottius Varieornatus and Hypsibius Dujardini after Exposure to UVC Radiation

Tue, 01 Jan 2013 00:00:00 +0000

Novel Middle-Type Kenyon Cells in the Honeybee Brain Revealed by Area-Preferential Gene Expression Analysis

Tue, 01 Jan 2013 00:00:00 +0000

Proteomic Analysis of the Royal Jelly and Characterization of the Functions of Its Derivation Glands in the Honeybee

Tue, 01 Jan 2013 00:00:00 +0000

Identification of Kakusei, a Nuclear Non-Coding RNA, as an Immediate Early Gene from the Honeybee, and Its Application for Neuroethological Study

Thu, 01 Nov 2012 00:00:00 +0000

Tolerance of Anhydrobiotic Eggs of the Tardigrade Ramazzottius Varieornatus to Extreme Environments

Sun, 01 Apr 2012 00:00:00 +0000

Detection of Neural Activity in the Brains of Japanese Honeybee Workers during the Formation of a Hot Defensive Bee Ball

Sun, 01 Jan 2012 00:00:00 +0000

Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade

Sun, 01 Jan 2012 00:00:00 +0000

Loss of Genes for DNA Recombination and Repair in the Reductive Genome Evolution of Thioautotrophic Symbionts of Calyptogena Clams

Sat, 01 Oct 2011 00:00:00 +0000

Suppression of the Immune Response Potentiates Tadpole Tail Regeneration during the Refractory Period

Wed, 01 Jul 2009 00:00:00 +0000

Inducible- and Constitutive-Type Transcript Variants of Kakusei , a Novel Non-Coding Immediate Early Gene, in the Honeybee Brain

Mon, 01 Sep 2008 00:00:00 +0000

Establishment of a Rearing System of the Extremotolerant Tardigrade Ramazzottius Varieornatus: A New Model Animal for Astrobiology

Sun, 01 Jun 2008 00:00:00 +0000

The Extracellular Adenosine Deaminase Growth Factor, ADGF/CECR1, Plays a Role in Xenopus Embryogenesis via the Adenosine/P1 Receptor

Tue, 01 Jan 2008 00:00:00 +0000

Identification of Novel Members of the Xenopus Ca2+ -Dependent Lectin Family and Analysis of Their Gene Expression during Tail Regeneration and Development

Sun, 01 Apr 2007 00:00:00 +0000

Increased Neural Activity of a Mushroom Body Neuron Subtype in the Brains of Forager Honeybees

Sun, 01 Apr 2007 00:00:00 +0000

[Molecular ethology using the honeybee as a model animal]

Wed, 01 Dec 2004 00:00:00 +0000

In Vivo Gene Transfer into the Adult Honeybee Brain by Using Electroporation

Sat, 01 May 2004 00:00:00 +0000

The Activity of Mblk-1, a Mushroom Body-Selective Transcription Factor from the Honeybee, Is Modulated by the Ras/MAPK Pathway

Thu, 01 May 2003 00:00:00 +0000

Identification of Genes Induced in Regenerating Xenopus Tadpole Tails by Using the Differential Display Method

Sat, 01 Feb 2003 00:00:00 +0000

Identification and Characterization of Mlr1,2: Two Mouse Homologues of Mblk-1, a Transcription Factor from the Honeybee Brain(1)

Wed, 01 Jan 2003 00:00:00 +0000

DNA-binding Properties of Mblk-1, a Putative Transcription Factor from the Honeybee

Fri, 01 Feb 2002 00:00:00 +0000

Identification of a Novel Gene, Mblk-1, That Encodes a Putative Transcription Factor Expressed Preferentially in the Large-Type Kenyon Cells of the Honeybee Brain

Mon, 01 Oct 2001 00:00:00 +0000

Regeneration of Sarcophaga Imaginal Discs in Vitro: Implication of 20-Hydroxyecdysone

Sat, 01 Mar 1997 00:00:00 +0000

國枝 武和 | 國枝研究室（生体情報学II）

A Versatile Technique for Measuring the Stiffness of Small Organisms Based on Microscopic Observation of Cantilever Strain

生命科学DOKIDOKI研究室にクマムシ研究のマンガと記事を掲載いただきました

【招待講演】小平市ふれあい下水道館30周年記念講演会

【招待講演】第36回変異機構研究会・特別講演

國枝武和教授が着任しました

Comparative Study of Gamma Radiation Tolerance between Desiccation-Sensitive and Desiccation-Tolerant Tardigrades

Sexual Dimorphism in the Tardigrade Paramacrobiotus Metropolitanus Transcriptome

Single-Step Generation of Homozygous Knockout/Knock-in Individuals in an Extremotolerant Parthenogenetic Tardigrade Using DIPA-CRISPR

The Major Inducible Small Heat Shock Protein HSP20-3 in the Tardigrade Ramazzottius Varieornatus Forms Filament-like Structures and Is an Active Chaperone

A Comparative Ultrastructure Study of the Tardigrade Ramazzottius Varieornatus in the Hydrated State, after Desiccation and during the Process of Rehydration

Considerations on the TardiVec-based Analyses of Tissue Specificity and Desiccation-Induced Supramolecular Structure of Target Proteins

Mblk-1/E93, an Ecdysone Related-Transcription Factor, Targets Synaptic Plasticity-Related Genes in the Honey Bee Mushroom Bodies

Application of CRISPR/Cas9 System and the Preferred No-Indel End-Joining Repair in Tardigrades

Stress-Dependent Cell Stiffening by Tardigrade Tolerance Proteins That Reversibly Form a Filamentous Network and Gel

Description of a Model Tardigrade Paramacrobiotus Metropolitanus Sp. Nov. (Eutardigrada) from Japan with a Summary of Its Life History, Reproduction and Genomics

Parallel Evolution of Trehalose Production Machinery in Anhydrobiotic Animals via Recurrent Gene Loss and Horizontal Transfer

Developmental Stage-Specific Distribution and Phosphorylation of Mblk-1, a Transcription Factor Involved in Ecdysteroid-Signaling in the Honey Bee Brain

Space Radiation Biology for Living in Space

Comparison of Sexual Reproductive Behaviors in Two Species of Macrobiotidae (Tardigrada: Eutardigrada)

Interleukin-11 Induces and Maintains Progenitors of Different Cell Lineages during Xenopus Tadpole Tail Regeneration

Comparative Genomics of the Tardigrades Hypsibius Dujardini and Ramazzottius Varieornatus

DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades

Gene Expression and Immunohistochemical Analyses of mKast Suggest Its Late Pupal and Adult-Specific Functions in the Honeybee Brain

Mblk-1 Transcription Factor Family: Its Roles in Various Animals and Regulation by NOL4 Splice Variants in Mammals

Acute Phase Response in Amputated Tail Stumps and Neural Tissue-Preferential Expression in Tail Bud Embryos of the Xenopus Neuronal Pentraxin I Gene

Extremotolerant Tardigrade Genome and Improved Radiotolerance of Human Cultured Cells by Tardigrade-Unique Protein

Novel Mitochondria-Targeted Heat-Soluble Proteins Identified in the Anhydrobiotic Tardigrade Improve Osmotic Tolerance of Human Cells

Suggested Involvement of PP1/PP2A Activity and De Novo Gene Expression in Anhydrobiotic Survival in a Tardigrade, Hypsibius Dujardini, by Chemical Genetic Approach

Unique Gene Expression Profile of the Proliferating Xenopus Tadpole Tail Blastema Cells Deciphered by RNA-sequencing Analysis

Splicing Variants of NOL4 Differentially Regulate the Transcription Activity of Mlr1 and Mlr2 in Cultured Cells

Identification and Characterization of an Egr Ortholog as a Neural Immediate Early Gene in the European Honeybee (Apis Mellifera L.)

Expression Analysis of XPhyH-like during Development and Tail Regeneration in Xenopus Tadpoles: Possible Role of XPhyH-like Expressing Immune Cells in Impaired Tail Regenerative Ability

Analysis of DNA Repair and Protection in the Tardigrade Ramazzottius Varieornatus and Hypsibius Dujardini after Exposure to UVC Radiation

Novel Middle-Type Kenyon Cells in the Honeybee Brain Revealed by Area-Preferential Gene Expression Analysis

Proteomic Analysis of the Royal Jelly and Characterization of the Functions of Its Derivation Glands in the Honeybee

Identification of Kakusei, a Nuclear Non-Coding RNA, as an Immediate Early Gene from the Honeybee, and Its Application for Neuroethological Study

Tolerance of Anhydrobiotic Eggs of the Tardigrade Ramazzottius Varieornatus to Extreme Environments

Detection of Neural Activity in the Brains of Japanese Honeybee Workers during the Formation of a Hot Defensive Bee Ball

Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade

Loss of Genes for DNA Recombination and Repair in the Reductive Genome Evolution of Thioautotrophic Symbionts of Calyptogena Clams

Suppression of the Immune Response Potentiates Tadpole Tail Regeneration during the Refractory Period

Inducible- and Constitutive-Type Transcript Variants of Kakusei , a Novel Non-Coding Immediate Early Gene, in the Honeybee Brain

Establishment of a Rearing System of the Extremotolerant Tardigrade Ramazzottius Varieornatus: A New Model Animal for Astrobiology

The Extracellular Adenosine Deaminase Growth Factor, ADGF/CECR1, Plays a Role in Xenopus Embryogenesis via the Adenosine/P1 Receptor

Identification of Novel Members of the Xenopus Ca2+ -Dependent Lectin Family and Analysis of Their Gene Expression during Tail Regeneration and Development

Increased Neural Activity of a Mushroom Body Neuron Subtype in the Brains of Forager Honeybees

[Molecular ethology using the honeybee as a model animal]

In Vivo Gene Transfer into the Adult Honeybee Brain by Using Electroporation

The Activity of Mblk-1, a Mushroom Body-Selective Transcription Factor from the Honeybee, Is Modulated by the Ras/MAPK Pathway

Identification of Genes Induced in Regenerating Xenopus Tadpole Tails by Using the Differential Display Method

Identification and Characterization of Mlr1,2: Two Mouse Homologues of Mblk-1, a Transcription Factor from the Honeybee Brain(1)

DNA-binding Properties of Mblk-1, a Putative Transcription Factor from the Honeybee

Identification of a Novel Gene, Mblk-1, That Encodes a Putative Transcription Factor Expressed Preferentially in the Large-Type Kenyon Cells of the Honeybee Brain

Regeneration of Sarcophaga Imaginal Discs in Vitro: Implication of 20-Hydroxyecdysone

國枝武和 | 國枝研究室（生体情報学II）